M8171-SID 852843说明书.pdf
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1、分子量373.38 溶解性(25C) DMSO 分子式C H N O SWater CAS号909859-19-4Ethanol 储存条件3年 -20C 粉末状 生物活性 SID 852843 is an inhibitor of West Nile Virus NS2B-NS3 proteinase. Flaviviruses, such as West Nile and Dengue, are a threat to humans from both public health and bioterrorism perspectives. The NS3 proteinase is ess
2、ential for flaviviral maturation. Inhibitors of NS3 are sought for treatment and prophylactic therapeutics. The NIH molecular library was screened for activity against West Nile Virus NS3, resulting in the discovery of SID 852843. This compound inhibits the NS3 proteinase of West Nile, but not of De
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