E3-Ligase-Ligand-Linker-Conjugates-24-TFA-DataSheet-MedChemExpress.pdf
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1、E3 Ligase Ligand-Linker Conjugates 24 TFACat. No.: HY-112617ACAS No.: 1957235-75-4Molecular Formula: CHFNOMolecular Weight: 576.48Target: E3 Ligase Ligand-Linker ConjugatePathway: PROTACStorage: 4C, stored under nitrogenSolvent & SolubilityIn Vitro 10 mM in DMSOConcentrationSolvent Mass 1 mg 5 mg 10
2、 mg1 mM 1.7347 mL 8.6733 mL 17.3467 mL5 mM 0.3469 mL 1.7347 mL 3.4693 mLPreparing Stock Solutions10 mM 0.1735 mL 0.8673 mL 1.7347 mLPlease refer to the solubility information to select the appropriate solvent.BIOLOGICAL ACTIVITYDescription E3 Ligase Ligand-Linker Conjugates 24 (TFA) incorporates an
3、E3 ligase ligand and a linker, can be an immunomodulater for the treatment of cancer.IC & Target Ligand for E3 Ligase1.REFERENCES1. ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1
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