1、LificiguatCat. No.: HY-14927CAS No.: 170632-47-0Molecular Formula: CHNOMolecular Weight: 304.34Target: Guanylate CyclasePathway: GPCR/G ProteinStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent all results are measured.MCE has not independently confirmed the accuracy o
2、f these methods. They are for reference only.www.MedChemE2REFERENCES1. Purohit R, et al. YC-1 binding to the subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the subunit. Biochemistry. 2014 Jan 14;53(1):101-14.2. Kong J, et al. YC-1 enhances the anti-tumor activity of sorafenib
3、 through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma. Mol Cancer. 2014 Jan 13;13:7.3. Chang LC, et al. YC-1 inhibits proliferation of breast cancer cells by down-regulating EZH2 expression via activation of c-Cbl and ERK. Br J Pharmacol. 2014
4、Sep;171(17):4010-25.4. Komsuoglu Celikyurt I, et al. Effects of YC-1 on Learning and Memory Functions of Aged Rats. Med Sci Monit Basic Res. 2014 Aug 21;20:130-7.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE3
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