1、MacitentanCat. No.: HY-14184CAS No.: 441798-33-0Molecular Formula: CHBrNOSMolecular Weight: 588.27Target: Endothelin ReceptorPathway: GPCR/G ProteinStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent 18(1):228.2. Sen S, et al. Renal, retinal and cardiac changes in type
2、2 diabetes are attenuated by macitentan, a dual endothelin receptor antagonist. Life Sci. 2012 Apr 13.3. Bruderer S, et al. Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist. AAPS J. 2012 Mar;14(1):68-78.4. Kim SJ, et al
3、. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist.Transl Oncol. 2012 Feb;5(1):39-47.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA BMC Cancer. 2018 Feb 6;18(1):154. Journal of Pharmaceutical Quality Assurance. 18 June 2015.www.MedChemE2