Macitentan-n-butyl-analogue-DataSheet-MedChemExpress.pdf
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Macitentan-n-butyl-analogue-DataSheet-MedChemExpress.pdf
1、Macitentan n-butyl analogueCat. No.: HY-14184ACAS No.: 556797-16-1Molecular Formula: CHBrNOSMolecular Weight: 587.28Target: Endothelin ReceptorPathway: GPCR/G ProteinStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent & SolubilityIn Vitro 10 mM in DMSOConcentrationSolve
2、nt Mass 1 mg 5 mg 10 mg1 mM 1.7028 mL 8.5138 mL 17.0277 mL5 mM 0.3406 mL 1.7028 mL 3.4055 mLPreparing Stock Solutions10 mM 0.1703 mL 0.8514 mL 1.7028 mLPlease refer to the solubility information to select the appropriate solvent.BIOLOGICAL ACTIVITYDescription Macitentan n-butyl analogue is a n-butyl
3、 analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1