Napabucasin-DataSheet-MedChemExpress.pdf
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Napabucasin-DataSheet-MedChemExpress.pdf
1、NapabucasinCat. No.: HY-13919CAS No.: 83280-65-3Molecular Formula: CHOMolecular Weight: 240.21Target: STATPathway: JAK/STAT Signaling; Stem Cell/WntStorage: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 monthSolvent Need ultrasonic and warming)ConcentrationSolvent Mass 1 mg 5 mg 10 mg1
2、 mM 4.1630 mL 20.8151 mL 41.6302 mL5 mM 0.8326 mL 4.1630 mL 8.3260 mLPreparing Stock Solutions10 mM 0.4163 mL 2.0815 mL 4.1630 mLPlease refer to the solubility information to select the appropriate solvent.In Vivo Napabucasin is prepared in PBS1.1. BIOLOGICAL ACTIVITYDescription Napabucasin is a new
3、ly found small molecule with the ability to inhibit gene transcription of STAT3, which is able to suppress cancer stemness properties and induce cell death.IC 5(6):1251-8.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA Cancer Med. 2016 Jun;5(6):1251-8.www.MedChemE2