1、蟌(彼封搀換封徇封彼封讀缁缀欀螏刀頀h萀椀匂蔄弖猖笖笖笖愀氀挀椀琀漀渀椀渀攀渀攀刀攀氀愀琀攀搀倀攀瀀琀椀搀攀刀倀爀愀琀吀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀瀀椀挀最椀昀愀氀挀椀琀漀渀椀渀攀渀攀刀攀氀愀琀攀搀倀攀瀀琀椀搀攀刀倀爀愀琀吀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀瀀搀昀尀尀愀愀戀搀愀攀洀夀洀倀昀昀匀琀瀀瀀栀夀漀最栀琀娀唀夀堀氀嘀砀攀嘀匀戀伀稀倀欀圀最儀愀氀挀椀琀漀渀椀渀攀渀攀刀攀氀愀琀攀搀倀攀瀀琀椀搀攀刀倀爀愀琀吀愀琀愀匀栀攀攀琀攀搀栀攀洀砀瀀爀攀猀猀挀戀愀愀戀挀愀搀戀挀戀愀氀挀椀琀漀渀椀渀攀渀攀刀攀氀愀琀攀搀倀攀瀀琀椀搀攀刀倀爀愀琀吀愀琀一漀夀倀漀氀攀挀甀氀愀爀漀爀洀甀氀愀脀蘠
2、舠舀蘠舠丠蔀耠传蔀舠匠舀舀茀传舀漀氀攀挀甀氀愀爀圀攀椀最栀琀吀愀爀最攀琀刀倀刀攀挀攀瀀琀漀爀倀愀琀栀眀愀礀倀刀倀爀漀琀攀椀渀一攀甀爀漀渀愀氀匀椀最渀愀氀椀渀最匀琀漀爀愀最攀瀀漀氀礀瀀攀瀀琀椀搀攀猀琀漀爀攀搀甀渀搀攀爀渀椀琀爀漀最攀渀匀漀氀瘀攀渀琀瀀椀渀搀甀挀攀猀愀爀愀瀀椀搀氀礀搀攀瘀攀氀漀瀀椀渀最洀椀渀愀渀搀氀漀渀最氀愀猀琀椀渀最栀搀漀猀攀搀攀瀀攀渀搀攀渀琀漀攀搀攀洀愀椀渀琀栀攀爀愀琀挀栀攀攀欀刀倀椀渀搀甀挀攀猀愀猀洀愀氀氀攀爀漀攀搀攀洀愀琀漀最攀渀椀挀攀昀昀攀挀琀椀渀琀栀攀爀愀琀栀椀渀搀瀀愀眀愀氀猀漀戀氀漀挀欀攀搀戀礀琀栀攀刀倀愀渀琀愀最漀渀椀猀琀刀倀瀀瀀漀琀攀渀琀椀愀琀攀猀琀栀攀漀攀搀攀洀
3、愀椀渀搀甀挀攀搀戀礀挀漀椀渀樀攀挀琀攀搀猀甀戀猀琀愀渀挀攀倀渀嬀崀倀爀漀搀甀挀琀愀琀愀匀栀攀攀琀渀栀椀戀椀琀漀爀猀最漀渀椀猀琀猀匠挀爀攀攀渀椀渀最椀戀爀愀爀椀攀猀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀漀洀倀刀伀吀伀伀渀椀洀愀氀搀洀椀渀椀猀琀爀愀琀椀漀渀嬀崀刀愀琀猀嬀崀愀氀攀圀椀猀琀愀爀爀愀琀猀眀攀椀最栀椀渀最最愀爀攀甀猀攀搀琀栀爀漀甀最栀漀甀琀琀栀椀猀猀琀甀搀礀猀猀漀漀渀愀猀琀栀攀爀椀最栀琀椀渀最爀攀昀氀攀砀椀猀氀漀猀琀琀栀攀椀渀椀琀椀愀氀琀洀攀愀猀甀爀攀洀攀渀琀漀昀挀栀攀攀欀琀栀椀挀欀渀攀猀猀椀渀洀洀椀猀洀愀搀攀眀椀琀栀搀椀最椀琀愀氀挀愀氀椀瀀攀爀猀琀栀攀椀渀琀爀愀漀爀愀氀椀渀樀攀挀琀椀漀渀最椀瘀攀
4、渀愀渀搀琀栀攀渀挀栀攀攀欀琀栀椀挀欀渀攀猀猀洀攀愀猀甀爀攀搀愀最愀椀渀愀琀愀渀搀洀椀渀愀渀搀栀昀漀氀氀漀眀椀渀最愀最漀渀椀猀琀猀愀氀挀椀琀漀渀椀渀攀渀攀刀攀氀愀琀攀搀倀攀瀀琀椀搀攀刀倀爀愀琀吀攀琀挀漀爀猀愀氀椀渀攀椀渀樀攀挀琀椀漀渀猀栀攀攀欀琀栀椀挀欀渀攀猀猀椀渀挀愀爀爀愀最攀攀渀愀渀椀渀樀攀挀琀攀搀愀渀椀洀愀氀猀椀猀洀攀愀猀甀爀攀搀愀琀洀椀渀愀渀搀栀倀愀眀琀栀椀挀欀渀攀猀猀椀渀洀洀椀猀漀戀琀愀椀渀攀搀猀椀洀椀氀愀爀氀礀甀猀椀渀最琀栀攀挀愀氀椀瀀攀爀猀愀琀琀栀攀琀椀洀攀瀀漀椀渀琀猀椀渀搀椀挀愀琀攀搀昀漀爀挀栀攀攀欀漀攀搀攀洀愀眀椀琀栀琀栀攀漀渀氀礀搀椀昀昀攀爀攀渀挀攀戀攀椀渀最琀栀愀琀琀栀攀愀
5、渀椀洀愀氀猀愀爀攀渀漀琀愀渀攀猀琀栀攀琀椀稀攀搀昀漀爀氀漀挀愀氀椀渀琀爀愀瀀氀愀渀琀愀爀椀渀樀攀挀琀椀漀渀猀嬀崀栀愀猀渀漀琀椀渀搀攀瀀攀渀搀攀渀琀氀礀挀漀渀昀椀爀洀攀搀琀栀攀愀挀挀甀爀愀挀礀漀昀琀栀攀猀攀洀攀琀栀漀搀猀吀栀攀礀愀爀攀昀漀爀爀攀昀攀爀攀渀挀攀漀渀氀礀刀刀一匀嬀崀匀栀愀琀琀愀攀琀愀氀愀氀挀椀琀漀渀椀渀最攀渀攀爀攀氀愀琀攀搀瀀攀瀀琀椀搀攀唀渀搀攀爀猀琀愀渀搀椀渀最椀琀猀爀漀氀攀搀甀挀愀琀椀漀渀愀氀漀爀甀洀嬀崀昀琀攀欀栀愀爀椀匀攀琀愀氀愀氀挀椀琀漀渀椀渀最攀渀攀爀攀氀愀琀攀搀瀀攀瀀琀椀搀攀刀倀愀渀搀椀琀猀爀攀挀攀瀀琀漀爀挀漀洀瀀漀渀攀渀琀猀椀渀栀甀洀愀渀愀渀搀爀愀琀猀瀀椀渀愀氀琀爀椀最
6、攀洀椀渀愀氀渀甀挀氀攀甀猀愀渀搀猀瀀椀渀愀氀挀漀爀搀愀琀氀攀瘀攀氀一攀甀爀漀猀挀椀一漀瘀嬀崀儀甀攀椀爀漀稀攀琀愀氀愀氀挀椀琀漀渀椀渀最攀渀攀爀攀氀愀琀攀搀瀀攀瀀琀椀搀攀椀猀愀瀀漀琀攀渀琀椀渀搀甀挀攀爀漀昀漀攀搀攀洀愀椀渀爀愀琀漀爀漀昀愀挀椀愀氀琀椀猀猀甀攀一攀甀爀漀瀀攀瀀琀椀搀攀猀瀀爀愀甀琀椀漀渀倀爀漀搀甀挀琀栀愀猀渀漀琀戀攀攀渀昀甀氀氀礀瘀愀氀椀搀愀琀攀搀昀漀爀洀攀搀椀挀愀氀愀瀀瀀氀椀挀愀琀椀漀渀猀漀爀爀攀猀攀愀爀挀栀甀猀攀漀渀氀礀吀攀氀愀砀洀愀椀氀琀攀挀栀攀搀栀攀洀砀瀀爀攀猀猀挀漀洀搀搀爀攀猀猀攀攀爀倀愀爀欀爀匀甀椀琀攀儀漀渀洀漀甀琀栀甀渀挀琀椀漀渀一唀匀眀眀眀攀搀栀攀洀砀瀀爀攀猀猀挀漀洀
7、攀搀栀攀洀砀瀀爀攀猀猀靓min, 1, 2, 3, 4, 5, 6 and 24 h. Paw thickness (in mm) is obtained similarly, using the calipers at the time points indicated for cheek oedema, with the only difference being that the animals are not anesthetized for local (intraplantar) injections3.MCE has not independently confirmed the
8、 accuracy of these methods. They are for reference only.REFERENCES1. S. Ghatta, et al. Calcitonin gene-related peptide: Understanding its role. Educational Forum. 20.6.2004.2. Eftekhari S, et al. Calcitonin gene-related peptide (CGRP) and its receptor components in human and rat spinal trigeminal nu
9、cleus and spinal cord at C1-level. BMC Neurosci. 2011 Nov 10;12:112.3. Queiroz BFG, et al. Calcitonin-gene related peptide is a potent inducer of oedema in rat orofacial tissue. Neuropeptides. 2018 Apr;68:43-48.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2MedChemExpress0001500006先进医疗20190529
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