Bobcat339-hydrochloride-DataSheet-MedChemExpress.pdf
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Bobcat339-hydrochloride-DataSheet-MedChemExpress.pdf
1、Bobcat339 hydrochlorideCat. No.: HY-111558AMolecular Formula: CHClNOMolecular Weight: 334.2Target: OthersPathway: OthersStorage: Please store the product under the recommended conditions in the COA.Solvent Need ultrasonic)ConcentrationSolvent Mass 1 mg 5 mg 10 mg1 mM 2.9922 mL 14.9611 mL 29.9222 mL5
2、 mM 0.5984 mL 2.9922 mL 5.9844 mLPreparing Stock Solutions10 mM 0.2992 mL 1.4961 mL 2.9922 mLPlease refer to the solubility information to select the appropriate solvent.In Vivo Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.17 mg/mL (6.49 mM); Clear solution1.
3、Add each solvent one by one: 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.17 mg/mL (6.49 mM); Clear solution2. Add each solvent one by one: 10% DMSO 90% corn oilSolubility: 2.17 mg/mL (6.49 mM); Clear solution3. BIOLOGICAL ACTIVITYDescription Bobcat339 hydrochloride is a cytosine-based TET enzym
4、e inhibitor with IC50 of 33 M (TET1) and 73 M (TET2). It is useful to the field of epigenetics and serves as a starting point for new therapeutics that target DNA methylation and gene transcription.IC 10(2):180-185.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAwww.MedChemE2