BzNH-BS-DataSheet-MedChemExpress.pdf
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1、BzNH-BSCat. No.: HY-111878Molecular Formula: CHNOMolecular Weight: 674.82Target: SNIPERPathway: PROTACStorage: Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITYDescription BzNH-BS contains two different ligands, methyl-bestatin (MeBS) for cIAP1 and benzoyl-amid
2、e, which are connected by linkers. MeBS as a ligand for cellular inhibitor of apoptosis protein 1 (cIAP1) ubiquitin ligase1.REFERENCES1. Ohoka N, et al. SNIPER(TACC3) induces cytoplasmic vacuolization and sensitizes cancer cells to Bortezomib. Cancer Sci. 2017 May;108(5):1032-1041.Caution: Product has not been fully validated for medical applications. For research use only.Tel: 609-228-6898 Fax: 609-228-5909 E-mail: techMedChemEAddress: 1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USAProduct Data Sheet InhibitorsAgonistsScreening Librarieswww.MedChemE1
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