KCA-757-DataSheet-MedChemExpress.pdf
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1、KCA 757Cat. No.: HY-14938CAS No.: 125961-82-2Molecular Formula: CHOSMolecular Weight: 530.67Target: Leukotriene ReceptorPathway: GPCR/G ProteinStorage: Please store the product under the recommended conditions in the COA.Solvent LTE4, pA2: 6.45 (In guinea-pigs)In Vitro KCA757 inhibits the binding of
2、 3H LTD4 to the LTD4 receptors on pul-monary cell membrane of guinea-pigs (IC50 = 2.3 mol)2.In Vivo Fiftheen min after an aerosolized antigen challenge, and UNDW inhaled 5 min later into the guinea pigs, KCA-757 significantly alters the UNDW-induced bronchoconstriction1. KCA757 (1 and 5 mg/kg) admin
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- KCA 757 DataSheet MedChemExpress