肺泡-动脉氧分压差在新生儿呼吸窘迫综合征中的应用价值分析.pdf
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1、47中国实用医药2023年8月第18卷第16期China Prac Med,Aug 2023,Vol.18,No.16间,而且所需支架直径更大,支架长度更长,可能会增加更多的手术风险,增加医疗负担。综上所述,处于 FFR 临界值的 CBL 患者采取单支架与双支架 PCI 治疗,心血管不良事件发生率无明显差异,但单支架 PCI 治疗肝素用量、造影剂用量更少,支架总长更短,支架直径更窄,手术时间与住院时间更少,而且可更好地改善术后生活质量,值得应用。参考文献1 王振胜,李才元,包全儒.血流储备分数评估老年冠心病患者介入治疗后分叉病变血管功能的研究.心肺血管病杂志,2021,40(5):426-43
2、0.2 丁成彦,胡桂菊.冠脉血流储备分数测定在冠脉分叉病变介入治疗中的应用价值分析.医药前沿,2021,11(28):43-44,47.3 陈杰民,兰军,涂昌,等.冠状动脉造影与血流储备分数指导下边支介入治疗对冠状动脉分叉病变患者影响的对比研究.实用心脑肺血管病杂志,2017,25(1):64-67.4 陈杰民,兰军,涂昌,等.血流储备分数对冠状动脉主支介入治疗时受累分叉病变血管功能的评估.中国临床研究,2017,30(5):623-625,630.5 杨慎先,杜梅花,王枫岭,等.血流储备分数对冠状动脉分叉病变 PCI 治疗策略的影响.中国心血管病研究,2015,13(2):141-144.6
3、 满万荣,陈青,张卫泽,等.血流储备分数在冠状动脉分叉病变介入治疗中的作用.临床心血管病杂志,2015,31(12):1319-1323.7 李飞,孙红梅,周静,等.血流储备分数在冠状动脉分叉病变中的应用价值.贵阳医学院学报,2015,40(9):1008-1009,1012.8 程飞,兰军,涂昌,等.冠状动脉分叉病变边支行血流储备分数测定的临床意义分析.中西医结合心血管病电子杂志,2016,4(21):62-63.9 周俊,杨鑫.血流储备分数对冠状动脉分叉病变 PCI 治疗措施的影响探析.中国保健营养,2018,28(28):86.10 王斌,赵巍,苏彦宾,等.介入治疗分支病变对主支病变血流
4、储备分数影响.临床军医杂志,2020,12(5):526-527.11 李巧春.不同策略在血流储备临界值时介入治疗的效果.中国老年学杂志,2021,41(18):3892-3895.12 王静,刘桂华,葛震,等.血流储备分数评估分叉病变单支架术后边支功能的研究.中国临床实用医学,2016,7(4):38-40.收稿日期:2022-11-28作者单位:515100汕头市妇幼保健院儿科(罗丹);515100霞浦福宁医院儿科(薛凤莲);515100民生医院新生儿科(陈晓东)肺泡-动脉氧分压差在新生儿呼吸窘迫综合征中的 应用价值分析罗丹薛凤莲陈晓东【摘要】目的探讨肺泡-动脉氧分压差(A-aDO2)在新
5、生儿呼吸窘迫综合征(NRDS)中的应用价值。方法选取 46 例 NRDS 患儿为观察组,另选取同期健康新生儿 46 例为对照组。比较两组胎龄和动脉血气指标A-aDO2、氧合指数(OI)、呼吸指数(RI),比较观察组患儿不同时间点的动脉血气指标,统计观察组患儿撤机后的预后情况,比较观察组撤机后生存和死亡患儿的动脉血气指标。结果观察组的胎龄(30.001.00)周小于对照组的(34.001.00)周,A-aDO2(45.6813.42)mm Hg(1 mm Hg=0.133 kPa)、RI(5.220.86)高于对照组的(18.651.56)mm Hg、(0.780.28),OI(178.638.
6、47)mm Hg 低于对照组的(330.647.56)mm Hg,差异具有统计学意义(P0.05)。观察组患儿机械通气前、机械通气 2 d 后、撤机前的 A-aDO2、OI、RI 比较,差异具有统计学意义(P0.05);且机械通气前、机械通气 2 d 后、撤机前A-aDO2、RI 依次降低,OI 依次升高,差异具有统计学意义(P0.05)。观察组患儿撤机后生存 41 例,死亡 5 例。观察组撤机后生存患儿的 A-aDO2(20.5810.45)mm Hg、RI(1.150.13)低于死亡患儿的(46.50 8.56)mm Hg、(4.580.28),OI(389.365.64)mm Hg 高于
7、死亡患儿的(175.447.56)mm Hg,差异具有统计学意义(P0.05)。结论A-aDO2可评估 NRDS 患儿的病情,能作为诊断和判断预后的指标。【关键词】新生儿呼吸窘迫综合征;肺泡-动脉氧分压差;应用价值DOI:10.14163/ki.11-5547/r.2023.16.011Application value of alveolar arterial oxygen pressure difference in neonatal respiratory distress syndrome LUO Dan,XUE Feng-lian,CHEN Xiao-dong.Department
8、of Pediatrics,Shantou Maternal and Child Health Hospital,Shantou 515100,China【Abstract】Objective To discuss the application value of alveolar arterial oxygen pressure difference(A-aDO2)in neonatal respiratory distress syndrome(NRDS).Methods 46 children with NRDS were selected 48中国实用医药2023年8月第18卷第16期
9、China Prac Med,Aug 2023,Vol.18,No.16as the observation group,and another 46 healthy neonates at the same period were selected as the control group.The gestational age and arterial blood gas indexes A-aDO2,oxygenation index(OI),respiratory index(RI)were compared between the two groups;the arterial bl
10、ood gas indexes of the children in the observation group at different time points were compared;the prognosis of the children in the observation group after weaning was counted;the arterial blood gas indexes of the children who survived and died after weaning were compared in the observation group.R
11、esults The gestational age of(30.001.00)weeks in the observation group was less than that of(34.001.00)weeks in the control group;A-aDO2 of(45.6813.42)mm Hg(1 mm Hg=0.133 kPa)and RI of(5.220.86)in the observation group were higher than those of(18.651.56)mm Hg and(0.780.28)in the control group;OI of
12、(178.638.47)mm Hg in the observation group was lower than that of(330.647.56)mm Hg in the control group;the differences were statistically significant(P0.05).There were statistically significant differences in A-aDO2,OI and RI before mechanical ventilation,2 d after mechanical ventilation and before
13、 weaning in the observation group(P0.05).In addition,A-aDO2 and RI decreased and OI increased successively before mechanical ventilation,2 d after mechanical ventilation and before weaning,and the differences were statistically significant(P0.05).In the observation group,41 children survived and 5 c
14、hildren died after weaning.In the observation group,A-aDO2 of(20.5810.45)mm Hg and RI of(1.150.13)of surviving children were lower than those of(46.508.56)mm Hg and 4.580.28)of dead children;OI of(389.365.64)mm Hg of surviving children was higher than that of(175.447.56)mm Hg of dead children;the di
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