BAY-61-3606-Syk-Inhibitor-MedChemExpress.pdf
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1、BAY 61-3606Cat. No.: HY-76474CAS No.: 732983-37-8分式: CHNO分量: 390.4作靶点: Syk作通路: Protein Tyrosine Kinase/RTK储存式: Please store the product under the recommended conditions in the COA.BIOLOGICAL ACTIVITY物活性 BAY 61-3606是活性 ATP竞争性,可逆的 Syk选择性抑制剂, Ki为7.5 nM,对 Btk,Fyn,Itk,Lyn 和 Src抑制性 。客户使本产品发表的科研献See more c
2、ustomer validations on www.MedChemEREFERENCES1. Yamamoto N, et al. The orally available spleen tyrosine kinase inhibitor 2-7-(3,4-dimethoxyphenyl)-imidazo1,2-cpyrimidin-5-ylaminonicotinamide dihydrochloride (BAY 61-3606) blocks antigen-induced airway inflammation in rodents. J Pharmacol Exp Ther. 22
3、. Lau KS, et al. BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner. PLoS One. 2012;7(7):e41343.McePdfHeightCaution: Product has not been fully validated for medical applications. For research use only.Tel: 400-820-3792; 021-58955995 Fax: 021-53700325 E-mail: techMedChemEMaster of Small Molecules 您边的抑制剂师Product Data Sheet InhibitorsAgonistsScreening Libraries Neuro Oncol. 2018 Apr 9;20(5):621-631. Front Immunol. 2018 Feb 15;9:249. Harvard Medical School LINCS LIBRARYwww.MedChemE1
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