二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇动态血糖、营养状况和妊娠结局的影响.pdf
《二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇动态血糖、营养状况和妊娠结局的影响.pdf》由会员分享,可在线阅读,更多相关《二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇动态血糖、营养状况和妊娠结局的影响.pdf(4页珍藏版)》请在文库网上搜索。
1、 药物与临床 糖尿病新世界 2023年9月DIABETES NEW WORLD 糖尿病新世界二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇动态血糖、营养状况和妊娠结局的影响罗秀芳浦城县总医院仙阳分院妇女保健,福建浦城 353400摘要 目的 观察二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇动态血糖、营养状况和妊娠结局的影响。方法 选取 2020年 4月2022年 5月浦城县总医院仙阳分院收治的 88例妊娠期糖尿病孕妇进行研究。采用简单随机分组法分为对照组和观察组,每组 44例。对照组孕妇在常规治疗基础上予以口服二甲双胍片,观察组在对照组基础上采用营养师根据孕妇个体化情况设计的膳食纤维饮食干预
2、,均干预至妊娠结束。比较两组孕妇干预前后的动态血糖、营养状况以及妊娠结局的变化。结果 干预后,观察组糖化血红蛋白、空腹血糖、餐后 2 h血糖水平均低于对照组,差异有统计学意义(P0.05)。观察组的微型营养评价量表评分、血蛋白、转铁蛋白水平均高于对照组,差异有统计学意义(P0.05)。观察组不良妊娠结局率为15.91%低于对照组的36.36%,差异有统计学意义(P0.05)。结论 二甲双胍联合膳食纤维饮食干预对妊娠期糖尿病孕妇血糖指标改善、营养状况提升和妊娠结局有良好作用,且安全性较高。关键词 二甲双胍;膳食纤维饮食干预;妊娠期糖尿病;妊娠结局中图分类号 R714 文献标识码 A 文章编号 1
3、672-4062(2023)09(a)-0083-04Effects of Metformin Combined with Dietary Fiber Dietary Intervention on Dynamic Blood Glucose,Nutritional Status and Pregnancy Outcome in Pregnant Women with Gestational Diabetes MellitusLUO XiufangDepartment of Women Health Care,Xianyang Branch of Pucheng County General
4、Hospital,Pucheng,Fujian Province,353400 ChinaAbstract Objective To observe the effects of metformin combined with dietary fiber dietary intervention on dynamic blood glucose,nutritional status and pregnancy outcome of pregnant women with gestational diabetes mellitus.Methods A total of 88 pregnant w
5、omen with gestational diabetes mellitus admitted to Xianyang Branch of Pucheng County General Hospital from April 2020 to May 2022 were selected for study.They were divided into control group and observation group by simple random grouping method,44 cases in each group.Pregnant women in the control
6、group were given oral metformin tablets on the basis of routine treatment,and the observation group was given dietary fiber diet intervention designed by nutritionists according to the individual situation of pregnant women on the basis of the control group,all of which were intervened until the end
7、 of pregnancy.The changes of dynamic blood glucose,nutritional status and pregnancy outcome before and after intervention were compared between the two groups.Results After intervention,the levels of glycosylated hemoglobin,fasting plasma glucose and 2-hour postprandial blood glucose in the observat
8、ion group were lower than those in the control group,and the differences were statistically significant(P0.05).The scores of Mini-Nutritional Assessment Scale,blood protein and transferrin levels in the observation group were higher than those in the control group,and the differences were statistica
9、lly significant(P0.05).The DOI:10.16658/ki.1672-4062.2023.17.083作者简介 罗秀芳(1975-),女,本科,副主任医师,研究方向为妇女保健方面研究。83 药物与临床 糖尿病新世界 2023年9月糖尿病新世界 DIABETES NEW WORLDadverse pregnancy outcome rate of the observation group was 15.91%,which was lower than that of the control group(36.36%),and the difference was st
10、atistically significant(P0.05),具有可比性。本研究经由本院医学伦理会审核通过。1.2 纳入与排除标准纳入标准:符合诊治标准5临床确诊;孕妇依从性良好能完成研究任务;孕妇无精神类疾病或认知障碍;孕妇没有接触过常规糖尿病治疗;孕妇知情并签署同意书。排除标准:有干扰营养指标和血糖指标的其他疾病孕妇;未成年或年龄45岁孕妇;孕妇临床资料不全或缺失;有合并其他重大疾病或者妊娠期并发症孕妇;对实验及药物过敏孕妇;体外授精或人工授精孕妇;有传染性疾病(如结核、艾滋病、梅毒)孕妇。1.3 方法两组孕妇均采用常规治疗方法干预,由护士和医师指导并讲解妊娠糖尿病基础知识,告知患者控制饮
11、食对妊娠期糖尿病的重要性,讲授日常饮食应注意事项以及科学搭配方案,由患者自主控制。对照组孕妇在此基础上予以口服二甲双胍片(国药准字 H22021184;规格:0.25 g)0.25 g/次,1 d/次,持续用药至妊娠结束。观察组在对照组的基础上加以本院营养师团队针对孕妇特性化情况制订的膳食纤维饮食干预:根据患者个体情况,在尊重患者饮食习惯的基础上,按照平衡膳食原则保证少食多餐,确保各项营养成分摄入达标,如每日摄入的碳水化合物、蛋白质、脂肪,比例为50%60%:15%20%:25%30%,并于每日早餐前和晚餐前食用复合膳食纤维食物(魔芋、燕麦、玉米等),避免过饥或者过饱,同时可以降低血糖峰值。控
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- 二甲双胍 联合 膳食 纤维 饮食 干预 妊娠期 糖尿病 孕妇 动态 血糖 营养 状况 妊娠 结局 影响